I don't want to encourage you to smoke weed while on Zoloft, but I did with no bad effects.

I was on Zoloft for a year, stopped, and now take 5-HTP which is available over-the-counter. Unless you have really bad symptoms or problems, I'd recommend trying 5-HTP for a while before starting with the Rx for Zoloft, or similar drugs. 5-HTP is a precursor to serotonin, and helps the body create it naturally.

You can stop taking 5-HTP without the withdrawal symptoms that many people get when suddenly quitting SSRI's.

It's just my opinon, based on my experience. I'm not a doctor or healthcare professional. Others have had similar experiences with SSRI's and 5-HTP.