Due to its highly lipophilic properties, anandamide crosses the bloodâ??brain barrier readily, avoiding the principal problem that plagued the endorphin hypothesis. Activation of central CB1 receptors by exogenous cannabinoids such as THC causes intense subjective experiences similar to those reported by endurance athletes such as analgesia, sedation (postexercise calm), anxiolysis, and a sense of well being.
http://www.cmcr.ucsd.edu/geninfo/Exercise_Piomelli.pdf

Summary: Your body produces its own chemical similar to THC, called "anandamide". These guys found out that anandamide is released while exercising. This explains why runners get high after running several miles.

Thanks, science!
moeburn Reviewed by moeburn on . Exercise is like smoking pot http://www.cmcr.ucsd.edu/geninfo/Exercise_Piomelli.pdf Summary: Your body produces its own chemical similar to THC, called "anandamide". These guys found out that anandamide is released while exercising. This explains why runners get high after running several miles. Thanks, science! Rating: 5