well when i take a downer (xanax, soma, and hydrocodone) i'll always drink a beer or two.....don't take my word for it cuz i'm not a doctor but i've never noticed anything bad after takinga pill or two and drinkin a beer. infact...just increases the effects....especially xanax....one time i snorted one xanax (please do not jump my ass and call me stupid for snorting....it's my nose and my health) then drunk a beer. chewed a half of xanax chased it with a shot of vodka, then chased the other half like it was with a screwdriver (orange juince and vodka..if ya don't know)