Quote Originally Posted by mrdevious
Believe me, I would LOVE it if i could get oxycontin, morphine, vicodin, any of that. Oxy and Vic do still have acetaminophen, but at that strength I'd only have to take 1 pill's worth rather than 4
Actually, Oxycontin has no tylenol in it. Oxycontin is a 2 phase dose of oxycodone alone. They say it is a continous release (hence the name, OXYcodone CONTINuous release) but it really releases half of the dose within 30 minutes of taking it and then the other half is released around 4-6 hours later, depending on the person. Percocet and Tylox contain oxycodone and tylenol. Percodan contains oxycodone and aspirin. All hydrocodone preparations contain tylenol but in varying degrees depending on the brand name or generic used. Norco usually has the lowest amount of tylenol while Lortab is middle of the road and Vicodin and Lorcet usually have the higher amounts of tylenol.

That's good to hear... kinda, but I hope my kindney's are good now. 1,300 is within liver tolerance, but it can cause liver failure at only 2,500. The reason 1,300 is still of great concern is because those doses are based on acute levels, not prolonged daily administration.
Just because something is metabolized or eliminated by your kidneys doesn't mean it is going to damage them. Celebrex and IBU are very safe drugs when it comes to your kidneys. Celebrex is a Cox-2 inhibitor and was designed to increase safety as well as reduce gastro-intestinal side effects. Many drugs in the NSAID (non-steriodal anti-inflammatory drugs) class such as Voltaren or Lodine or Naprosyn work great for the pain but can cause stomach sensitivity if taken for long periods of time. There is almost zero incidence of stomach problems with Celebrex. IBU is a NSAID but it is still very gentle on the stomach.

Going back to the tylenol and the liver, actually the longer you take tylenol, the easier it is on the liver in many cases. Like Birdgirl said the liver is a very strong and resilient organ. I am sure you are aware that hydrocodone is abused by many people and I know of people who at the height of their abuse have taken nearly 100 sometimes 150 pills a day. That is easily enough tylenol (30-100 grams depending on the type of hydrocodone and how many) to cause death but with prolonged use the liver finds new metabolic pathways to eliminate tylenol from the body. You would think that those that have abused hydrocodone for long periods of time would have livers that look like swiss cheese but that is usually not the case.

Tramadol was brought to market as a painkiller with a lower potential for abuse. Most people do not abuse it but there is a potential for abuse. It is not physically addictive however. Just because you take it for long periods of time doesn't mean you will abuse it or become addicted to it. As far as signs of abuse or addiction, if it is interferring with your life or you become obsessed with tramadol, then those would be glaring signs. It is hard to say what the signs are because if you use it the way you are supposed to and you are not predisposed for addiction (such as family history of addiction or alcoholism) then there is not much to look for.




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