Are you talking about drying out a fresh bud for a sample? You can dry out a sample in the micro just do it at 30-40sec. intervals with like a 10 sec pause between dry times. Check it each time so you don't make it to crisp.Your sample won't be so great tasting or should I say not as good if you were to dry/cure them right.The only reason to use a micro is to get a quick fix through your time of need while waiting for the rest to dry properly.So yeah it will work but won't really gauge what your buds taste like or even the head you get from them. Other then that DON"T nuke your buds . Peace :hippy: