I have actually not smoked these strains yet. However, many different strains of cannabis help with my bp disorder. When I know that I am about to go into a manic phase, I try to get ahold of an indica to help chill me out and get some sleep. Sativas (like Kali mist for ex) I use for getting things done and concentration when the depressive fog rolls in. I have tried many different prescription drugs - all of which gave me horrible side effects. I'll stick with natures cure fo sheezy.