i know i am not who you are asking, but yes you would at least need to ventilate it. you are trying for healthy mothers to keep you in clones. i am new to this part but i think i am doing pretty well. i just cloned out a mom, not a big one, and got 15 decent clones from her plus a nice branch left on her to flower with the clones that i had started earlier. now i have 5 clones from earlier and 2 will be mothers for the next time through and probably get flowered as well. my light is too small to have to many under it so these 4 will be fine i think. i am thinking a little bigger now though since i should be getting a bigger light very shortly. the mom plant wasnt all that big and was lst'd to promote more cloning sites. flourescent lights and a closet or box should be enough to keep some healthy moms, if it was big enough you could also start your clones in the same closet/box.