I think on average no they will not get you high but if you already have a chemical imbalance (which is why you take anti-depressnts, bp meds, etc) it might balance you out making you feel happier (because your feel good nuerotransmitters like serotonin, norephedine (sp?), dopamine, and GABA are at the right levels) but otherwise your are wasting time/money. BUT I take anti-depressants and when I used to take Celexa I felt like I was rolling balls!! actually that is why I quit taking it because it was cool when I was at home or something but NOT COOL at school or work.