"Two papers with Dr. Carlos Gutierrez-Noriega reported the effects of oral administration of this alkaloid in doses varying from 5 to 11.5 g per kilo in 43 subjects, of whom developed a brief psycotic state. The method of preparation of the alkaloid, some of its physical and chemical properties, the psychological changes, as well as the dosage of the alkaloid employed, suggested the presence of mescaline."

"The only other reference to opuntia cylindrica we have been able to find is in a review artical by Buscaino"

"We have been able to identify the alkaloid present as mescaline, present in a concentration of 0.9% of the whole dried plant. There is no more than a slight trace of additional alkaloids."

-Received March 21, 1960