Unless you have a .0000 scale with 2c-e, it can be pretty dangerous because 4mg off and it'll double the intensity of the trip, not like it's a bad thing, but for someone that isn't very experienced with psychedelics 2c-e can haunt your mind and freak you out. The amazing colors, colors that don't exist on this plane.......absolutely amazing. Side effects aren't that bad, nowhere near as bad as Ecstacy.