Hey,
One way to control the space you need for your mamas is to just cycle them through every so often... A flowering mom is a beautiful sight!
Overusing a mom... it is possible to get mutations from a really OLD mother, especially if she is stressed, the cut sites will have failures in DNA repair and lead to weird shit in future clones.
My recommendation is to take some of your clones and start NEW mothers and flower the old ones, and to post pics!