in Ocarina of time i was in the water temple and i was playing at my friends house, and somehow it got saved at a terrible time. the temple was flooding and i had already made a mistake. so i had to commit suicide, but it just brought me back to where it was saved, which is after the part i needed to get to was flooded. so i either had to give up the game or start from the begining. i quit.

that also happened to me in Red Faction. there was a countdown to an explosion and i had to get out of a building before it went off. but i saved it with a minute left on the countdown(it started with like 2) but since i was alreayd behind schedule, it was impossible to make it out.