Nah... Don't preface it with "can we talk for a second" - That takes the nonchalance out of it. We ladies know damn well that that is the man-version of "We need to talk." *shudder* *wink*

When you're just hanging out and mellow, toss it out there. If you can't find an opening, make one - Mention a couple you know who just started dating: "Hey, did you hear that Jenna and Mike are going out now?" That way your question will be relative to the conversation.

Yeah, don't do it when you're drunk or high. If all goes well, you don't want either of you to be left wondering the next day if it was the alcohol talking. And in any case, you're less likely to pull off the casual delivery if you're not on your game.