I get viciously ill if I dont take my meds. Like rolling on my bed crying. sweating, and shaking. I take alot of meds, Lithium 2 times a day 250mg each, Serequil 1,000mg Once at night and trazadone 100mg once a night. Weed affects my meds a little bit, makes my trazadone less affective but besides that i'm fine.