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11-30-2006, 07:19 PM #1
Senior Member
So, to dispel this common rumor
Well, it could be psychosomatic because the first few times she was probably worried or paranoid about it. I know that sometimes I get a lot more fucked up than others when I have smoked so much more. It's weird I really do think it all depends on the mood/setting. Oh and lack of sleep hahaha. I don't know though. Been so long since I smoked the first time. I remember it but I had smoked a 7gram blunt with my brother on my b-day so I was baked my first.
Kilo0192 Reviewed by Kilo0192 on . So, to dispel this common rumor You know how some people don't get high their first time? Well, I had been reading that it was because the Cannabinoid receptors aren't active yet. Well, that isn't true. We have the cannabinoid receptors because we have endocannabinoids that use these receptors. THC just happens to be an agonist of these molecules. These receptors are always active due the fact that endocannabinoids are important in regulation of important bodily functions. THC binding to these receptors don't need a Rating: 5
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