is it possible to not be able to get high?

[birdgirl73]

It happens in some people, and I'm pretty well convinced it's because it takes longer to "activate" the cannabinoid receptors in some people's brains than in others. It took me almost that long to get high when I first tried grass in college, and I knew perfectly well how to inhale. Eventually, with persistence and repeated exposure, it worked.

[LazySmoking420]

If enough THC reaches the lungs, It'll produce a euphoric high to the brain that no human could resist.

Sounds like a high Tolerance problem.

[Frivolous248]

Two words.

GRAVITY BONG.

The only people who I've ever heard say they got high their first time said they took gravity hits. It makes sure you get a fat hit, and makes sure you inhale. If he still don't get high after 3 gravs...hes not gonna get high. Just make him pull them for himself until he feels done.

I'm convinced that is a fool-proof method to getting new smokers high. You'll be able to tell when hes havin' trouble packing the bowl and pulling it.

[graph]

It happens in some people, and I'm pretty well convinced it's because it takes longer to "activate" the cannabinoid receptors in some people's brains than in others. It took me almost that long to get high when I first tried grass in college, and I knew perfectly well how to inhale. Eventually, with persistence and repeated exposure, it worked.

I'm gonna hate it if you're gonna make me cite my sources on this one, but I'm pretty sure it has to do with the CNS. Everything that enters your brain has to do so through the spinal cord. Now, the thickness of the axons of the neurons in the CNS (ouch) vary from person to person, and also play a role in how well the stimulus is received. The cannabinoid receptors are rarely used except in the agonizing/antagonizing by the cannabinoids, and because of this, sometimes the message can be lost. It's also thought that certain cannabinoid receptors for lesser cannabinoids, of which make up the indica high, are not as strong until the user has experienced a "high". That had to do with how the cannabinoid receptors are located in the hypothalamus, but that thought also used a lot of big words that I can't remember.

I wrote that in a psychology paper a while back. I got an A on it, but for all I know I could have been BSing back then, too.

[getcrunk]

yea the dude wasnt inhaling right but he took in smoke and he should have at least gotten a little buzz.

[juicy james]

yeah i have noticed that the people who "cant" get high are the ones that you usually have to persuade them to even smoke in the first place. if they dont really want to smoke they wont get high because they will take baby hits and wont inhale. i have learned my lesson with people like that and i dont offer people weed anymore. when you see me puffin on a blunt all you have to do is ask and you'll get a shotgun. but i'm not gonna offer you weed because if you didn't ask you obviously dont want to get high.

[Paramik]

I ono if u have a good perception and can resist pschological effects good then hhe needs to smoke more potent stuff.