My brother has a similar problem with retina issues since birth. When he was 9, his retina detached, and it was a hellish experience for him, since we were overseas at the time....he started seeing purple in his vision and he had to be flown back to the states right away for surgery. I can't say if it would aggravate it, however he's been smoking marijuana for years without any signs of retina detachment. Infact I'm interested to know if it does indeed aggravate it. It's hard to say for certain because a lot of factors could lead to retinal detachment like getting hit in the head the wrong way, or the pressure from riding a roller coaster. Good question tho.