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10-05-2006, 11:38 AM #19
Senior Member
Sleeping Pills
Originally Posted by birdgirl73
nya nya.In the 1960s it was found that diphenhydramine (trade name Benadryl) inhibits reuptake of the neurotransmitter serotonin. This discovery led to a search for viable antidepressants with similar structures and fewer side effects, culminating in the invention of fluoxetine (Prozac), a selective serotonin reuptake inhibitor (SSRI). A similar search had previously led to the synthesis of the first SSRI zimelidine from chlorpheniramine, also an antihistamine.
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