I agree with the "cannabinoid receptors have to be awakened" theory, but there are two options that I believe may increase the risk of getting high the first time consuming cannabis.

1.) Eat it, don't smoke it
2.) If you do smoke it, smoke A LOT. Just have them take as many rips as possible until they're lungs are burning up to an almost unbearable degree. That, I think, would get just about anyone high their first try.
IllusionalFate Reviewed by IllusionalFate on . What causes the first time to have no effect? I have a close friend, and we may have an opportunity in a month to have her smoke for the first time (Her parents are very strict and we're going to a concert which will take all day). It is the only opportunity we will have for a while, so I want to make sure it works for her the first time. I do know that many first-time users don't get high, so what I would like to know is, what are some things we can do to lessen the chance of her not getting high the first time? Thanks in Rating: 5