Quote Originally Posted by MySignature
Chronic administration of Opiods (morphine, codeine, heroin, oxycodone, hydrocodone, methadone, tramadol, Phenylpiperidines, Diphenylpropylamine derivatives, Benzomorphan derivatives, Oripavine derivatives, Morphinan derivatives, et al) is, in fact, down-regulating the tuorachidonalglycerol, which is one the endocannabinoids.
There's no reason to smoke weed when you're counteracting the effects with all these drugs.