If you dont wanna look all druged out when your older, dont use drugs long term,weed might make you look a little drugie-ish when your older, but thats only long-term use and im talking like 20 30 years..

Other drugs, like harder stuff u should not use long term, cus it hurts your brain after a while.

Thats wut i know, Ive also watched a video on your brain and drugs and the biggest thing that the video said was, It is proven long-term use of any drug can make you loose some of your personality and you will not act like your normal self.