I've done ketamine as powder twice so far with doses of 70mg and 100mg. The latter one gave a lot more psychedelic experience (no wonder since the dose was closer to the usual average of "K-hole"). With both times the comedown has been somewhat queasy, the ketamine leaving me feeling fumbly and numb.

The trips were interesting with a whole different character compared to, for example, tryptamines. I was at times almost totally unaware of my body and at other times my body felt unfamiliar. Eyes open, the distances and proportions shifted. Eyes closed, I was presented with an astounding play of objects and ideas. With 70mg I wasn't getting much out of it, but with 100mg the trip was intense, but in a good sense.

Second time I did it I smoked some cannabis at comedown and found it to be of great assistance when adjusting back to normal world. I also found it nice to have a sitter present, that way I was able to let go of my body totally without having to think if it were going to be ok while I was travelling through the world that was unraveling before my closed eyes.