Sinicuichi is great, but it wont "fuck" you up, it's just a good experience. The only problem is online vendors sell the dried plant which isn't really good for much, you need the fresh material to feel good effects.

Amanita Muscaria scare me because many are extremely poisonous, i don't trust vendors to get me the right stuff. I heard the negatives outweigh the positives for most people.

Don't fuck with ayahuasca, it's an extremely powerful hallucinogen and it's not something to just get high with... it's extremely spiritual and if you don't treat it that way it will be the worst experience of your life.