YES! thats my perferrd method of self medication...... the 2x2 method. first you start rolling 2 blunts, while your doing that make yourself a drink and take 2 perks. smoke the blunts, and drink 2 drinks, while the 2 perks are kicken in. If you were sick, you feel better, if you had a pain (back, knee, elbow) it's gone, and if your depressed at all .... GONE!