well, my brother gave me five of them one time and i chewed them up (chewing/breaking up pills usually helps it hit yoru system harder/faster, but unless you know hwat you're doing i wouldn't suggest doing this, doing this with alot of medicnies could have negative reprecussions...) didn't do shit to me... so i'd safely say no... 1 isn't going to do shit to you... if this friend says he gets fucked up off of 1, slap him... cuz he's just trying to get attention or something along those lines, no way is 1 T3 going to fuck you up, atleast really good..