As long as they are all good strains of well grown bud, the only thing that will really happen is you will get more fucked up. I have have had really strong sativas with really strong inidcas you get everything as once it's almost like floating....really you can be hight two ways at once i believe. when you have a mixed sativa/indica strain they are good but you don't get everything as if you had them each as awhole ,, not jsut some characterists in them such as a hybrid strain.... i hope thatmakje s sense but you just get more fiery fun time...word