depending on what you're taking it for, you could always skip a dose, i wouldn't recommend doing this unless you know what you're doing (what stopping the specified medication abruptly can do, knowing your problems and how able you are to control them ect. ect...) i've known other people on that medicine.... and the only thing i could reallly say any of them have might of been a very mild case of depression... (not while skipping/missing doses, just in general mental disorders) so i dunno, it'd depend what you're on it for, and how severe it is... my depression is probably 3-4x theirs and i'm not even on medication for it..