Highschool is the pinnacle of failure in the American education system. You are not supposed to learn anything. It is constructed so that the people of lower intelligence can keep up with the watered down material, thus suffocating anyone of moderate intelligence. Your best bet is to go with the flow of the system, but make it interesting for yourself. Opinions are supressed so express them! Critisize everything. Question everything.

Do not participate in any school related programs though, this will only waste your time. Create your own extracurricular activities like reading or poetry or music, something that will possibly give you something useful for your future. Get a job. Not those bullshit fast-food/grocery types. Do something that goes against the grain of your typical highschooler. Work at the library or maybe a nursing home. This will give you a positive environment in the sense that you are around mostly intelligent people, or you are helping persons in need, etc. Save your money, ask youself if you really need that pair of pants, or if you really want or need that CD. Save your money I can not stress this enough.

Don't worry about love or friends, it's like Void mentioned, they are most definitely going to grow stale after you graduate anyway if not years earlier. I have outgrown most of my old friends from middle school and early highschool or they have dropped out and are still at home living on their computers.

Other than that simply concentrate on self-discovery and other interests you may have because there millions of things you could find interest in that will never be acknowledged in school.