Yeah alcohol makes you drunk because it is a poison. Marijuana merely binds to receptors in your brain that you already have, and you actually make your own cannabinoids, that's why people have those receptors. Opiates are similar, but of course too much heroin will kill you. But anyhow, alcohol is a toxin, plain and simple. And nicotine is officially classified as a poison by the way. Sure it's also a plant chemical, but it's a poison as well. Cannabinoids make a great drug because of their non-toxicity. And if you don't believe that alchohol is a poison, go slam a fifth of whisky and see how you feel.