Give that you take tylenol every four hours, it probably leaves the body quickly, otherwise it would build to toxic levels over a course of several days. I dought it is comepletely gone in 24 hours, few things are. These are only semi-educated guesses.
andruejaysin Reviewed by andruejaysin on . How long does acetaminophen stay in your system? I found a bottle of liquid hydrocodone a few days ago, and had probably more than I should have for two days in a row. :) I'm a little worried about the acetaminophen that's mixed in, so I didn't have any today. How long does acetaminophen stay in your system? Would it be completely gone after 24 hours? Rating: 5