Quote Originally Posted by Edgar
Actually, salvia is not as big of a mystery as it once was. I assume you're talkin' about serotonin in that first sentence, in which case your understanding of how salvia works is incorrect. Salvinorin-a (main active ingredient in salvia divinorum) is a kappa opioid receptor agonist, meaning that it binds to the kappa opioid receptors and triggers a response in the cells that those receptors are on. Kappa opioid receptors like most if not all receptors in our bodies have corresponding naturally occuring substances (endogenous ligands) that bind to them, for Kappa opioid receptors those substances are dynorphins.

http://en.wikipedia.org/wiki/Salvia_divinorum

http://www.pubmedcentral.nih.gov/art...medid=12192085
Edgar stop ruining everyone's fun.

Seriously folks, drugs are where you go when you die.

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ADaisyChain Reviewed by ADaisyChain on . Salvia rumour Well im not so sure if its a rumour or not, but ive heard a few times that salvia releases chemicals in your brain which only get released while your dying. This seems very strange, because if its true, mabye it causes us to see the spirtual world? I've also heard over a hundred times "mushrooms make your brain bleed" I know this one can't be true, but my question is do you think highly hallucinagenic drugs put us so over the edge, we are entering a different world, or reality, and that reality Rating: 5