^Yes. DXM and fluoxetine are also metabolized primarily by the same enzyme CYP-2D6. Furthermore some people are CYP-2D6 deficient and the result is slower metabolism of DXM/fluoxetine, such may explain an abnormally long duration of effects.
Nullific Reviewed by Nullific on . Weird drug interaction. Yesterday at 4:30 PM i took 600 mg of DXM and I was blasted until i went to bed at about 11:15. When I woke up, i just felt a little buzzed, which is normal for me when i wake up after DXM. Then i took my prozac (i skipped the dose the morning i took DXM) Like half way into first period i got like a hella social high. Im ruling out the placebo effect because ive experienced it and this was way different. With the placebo effect it goes on for like 30 mins and all i get is laughing. I Rating: 5