Hiya

Anti depressants partially or completely block the effects of ecstasy.
Combining MDMA with MAOI antidepressants is dangerous because it can easily lead to serotonin syndrome, which can be fatal.

Combining MDMA with SSRI antidepressants isn't as risky, but most SSRIs block the effects of MDMA anyway, so combining the two is pointless - I was given anti depressants a few years ago and when I took E, nothing happened
Now I only use the prozac after I am coming down off the E because it makes the come down more bearable the next day.
But yeah, if you have depression its probably not a good idea taking E anyway, you will feel on top of the world for the night but the next day is hell!

It leads to seratonin depletion if you abuse it so if you are going to take it, use it in moderation :thumbsup: