Also known by such street names as "jaster" and "silly salt." Instantly addictive drug derived from a tree only known to grow on a single planet. Affects entire nervous system, causing intense pleasure. Withdrawal is excruciatingly painful, and usually fatal; treatment requires total life support. It is said that an addict will gladly sell everything he or she owns, along with all body parts beyond the minimum needed to inject the drug, for his or her next dose. There is no known way to synthesize it, and the tree from which it is derived was thought to have been deliberately driven to extinction, but drug has reappeared. A large dose was used to defeat the malevolent entity known as the Vom.

Bloodhype --- Alan Dean Foster's Humanx Commonwealth

And you thought crackheads were bad? lol