well... for me... i used to get panic attacks when i smoked in the cold... i cut back on my smoking, and wouldnt smoke from late october untill about march...

but that seems to have stopped... it is also advised, in a spiritual-medical book i've read, not to take certian drugs in certian weather conditions...

cold = much more potent
warm = good
hot = less potent

and i think moisture conditions also greatly impact this.