true or false

[BobBong]

No, I'm not gonna. Mats and Rice don't built up a tolerance.

and ...

According to the U.S. Institute of Medicine (IOM), when examining drug addiction, tolerance, dependence, and withdrawal are the characteristics most often assessed to determine whether or not an addiction is indicated. Although some users of marijuana may experience slight tolerance, dependence, or withdrawal associated with use, the IOM argues that this is not evidence that marijuana is addictive. The organization asserts that tolerance and dependence are normal physiological adaptations to repeated use of any substance, including prescription drugs. Safe, appropriate use of many prescribed medications -- for pain, anxiety, hypertension, etc. -- routinely produces some level of tolerance and a slight physiological dependence that is addressed through dosage and may lead to withdrawal symptoms if stopped abruptly, rather than gradually.

The IOM also reported that observable symptoms attributed to marijuana withdrawal are rare and were only identifiable in "unique patient settings... limited to adolescents in treatment facilities for substance abuse problems, and in a research setting where subjects were given marijuana or THC daily." Compared to the withdrawal associated with alcohol or heroin, the marijuana-related symptoms of restlessness, irritability, and sleep disruption are minor. According to reports, the symptoms are not "severe enough to re-initiate use of cannabis." The criteria of tolerance, dependence, and withdrawal, therefore, do not indicate marijuana addiction, assert proponents of marijuana legalization.

http://www.kqed.org/topics/news/pers...juana/1no.html

I knew you'd come through :smokin:

[daZenfmeister]

The IOM that sounds so fucking fake

[DazedandConfused]

whats the difference between a physiological tolerance and a psychological one? its true that you dont build a physiological one but some tend to build a psychological one right?

so my guess would be that if you get it out of your head that you arent getting as high anymore, then youll be able to get as high as you used to right?

[Flesh420]

who cares about tolerence just smoke different strains and u should be good. At least thats how it works for me

[maskedpantsman]

dammit, now I have to change my avatar.

[Lily420]

"tolerance
Tolerance builds up rapidly after a few doses and disappears rapidly after a couple of days of abstinence. Heavy users need as much as eight times higher doses to achieve the same psychoactive effects as regular users using smaller amounts. They still get stoned but not as powerfully."

Thats bullshit

[beachguy in thongs]

The IOM that sounds so fucking fake

"The capacity to produce reinforcing effects is essential to any drug with significant abuse potential." Marijuana should no longer be considered a serious drug abuse because, as summarized by the OTA: "Animals will not self-administer THC in controlled studies . . . . Cannabinoids generally do not lower the threshold needed to get animals to self-stimulate the brain regard system, as do other drugs of abuse." Marijuana does not produce reinforcing effects. The definitive experiment which measures drug-induced dopamine production utilizes microdialysis is live, freely-moving rats. Brain microdialysis has proven that opiates, cocaine, amphetamines, nicotine and alcohol all affect dopamine production, whereas marijuana does not. This latest research confirms and explains Hollister's 1986 conclusion about cannabis and addiction: "Physical dependence is rarely encountered in the usual patterns, despite some degree of tolerance that may develop." Most important, the discoveries of Howlett and Devane, Herkenham and their associates demonstrate that the cannabinoid receptors do not influence the dopamine reward system.

http://www.druglibrary.org/schaffer/hemp/BRAIN.HTM

"More good fathers and mothers have lost the God-given right to be with their kids due to inappropriate marijuana laws than due to physical abuse. That is INSANE. In divorce battles, judges routinely ignore a parent's moderate alcohol use. Why not ignore moderate marijuana use by responsible people ? Marijuana use by non-criminal persons should have no criminal penalties associated with it whatsoever ! NORML Canada will settle for nothing less. Any criminal penalties for marijuana possession open the door for all sorts of smears, blackmail and dishonesty in many forms. Nobody deserves that !" -Umberto

It's fucken hard to understand where some fucken people come from when they say shit like "fucking fake".

[STDzRus]

Good thread.

Tolerance builds up just think about it.

Your body is used to having a new amount of chemicals in it's system, so in return it says "hey this must be normal" so it becomes adept to these high levels of chemicals. So it takes more to produce the effects as opposed to not having any of these chemicals in your system.

[psychopixi]

I notice my tolerance building up... and going down again. Finding a decent, reliable dealer in this area is getting difficult now, so we tend to pick up one week, then have nothing for the next three.

[somebody someone]

Yeah its true, to a degree. I would say regular users may need upto 3x the amount at times maybe but nowhere near 8