Great suggestions all.
I had not considered keeping it sealed. The reason I was thinking I need ventilation is so the heater (it gets cold here) can function properly. I would think it would use up the available oxygen during combustion.
What if I install the intakes for the cooled hoods in the floor. Let them suck the air from under the container which will always be cool and then let that exhaust inside the container.

Then there would be a steady supply of fresh air and the AC would keep it cool and control humidity during the summer. During the winter the heat from the lights would be supplemental heat for the heater.

If its sealed though I wonder how efficient the hood fans would be. No place for the air to go. Hmm....
Would a CO2 system be functional with ventilation?

This is the AC I plan to use:
http://www.grainger.com/Grainger/wwg...553432&ccitem=
This unit needs to exhaust the warm air outside in order to function. Perhaps this is the answer to air exchange?
Again the question "would CO2 system be efficient with this?"

This is the heater I plan to use: http://www.grainger.com/Grainger/wwg...541187&ccitem=

Zandor I plan on a dirt grow. Not very familiar with hydro. Read a lot about it but never tried it.
You mentioned earlier about 2 or 3 rooms. What would you recommend? I had figured on keeping mom and her clones together and moving the clones into the flower room as they mature. To make 3 rooms would be easy.

Thanks for all the good suggestions. I am thrilled with the response!

Joel I will see about getting some pics. I will definitely take pics of the build out and the grow.

Ciao