Orellanin: Consumption of mushrooms containing this toxin has the longest delayed reaction before the appearance of symptoms. Nausea, vomiting, diarrhea and anorexia present in most patient 12 hours to 3 days after consumption. In cases where poisoning was severe, evidence of renal damage occurs (burning thirst, frequent urination) may not occur until 3-15 days after consumption of mushroom. In mild poisoning cases, symptoms sometimes did not appear until 10-17 days after eating the mushroom.

Mushrooms containing Orellanin include: some species of Cortinarius, e.g., C. orellanus, C. speciosissimus, C. splendens