Lexapro is known to cause some dependency. Zoloft had hardly any side effects nor did I feel dependent on them after I quit taking them. the only thing was the sexual side effects. Anti-depressants DO work, it is the only thing that got me through post partum depression. It was the best thing I did for myself. I personally believe that you should only take them if you're in a situation that's causing you excessive stress/worry/fatigue. Just to help you get through the tough phase. Then you should definitely wean yourself off of it.