Brain use

[beachguy in thongs]

That's a natural high!!! Anyways, I made this through Wikipedia:

This is a list of what the receptor interacts with.

basal ganglia are a group of nuclei in the brain associated with motor and learning functions

The limbic system is a group of brain structures that are involved in various emotions such as aggression, fear, pleasure and also in the formation of memory.

(which affects),

The endocrine system is a control system of ductless endocrine glands that secrete chemical messengers called hormones that circulate within the body via the bloodstream to affect distant organs.

and

In contrast to the voluntary nervous system, the "involuntary" or autonomic nervous system is responsible for homeostasis, maintaining a relatively constant internal environment by controlling such involuntary functions as digestion, respiration, perspiration, and metabolism, and by modulating blood pressure.

ALSO:

Cannibinoid receptor are found in:

The cerebellum (Latin: "little brain") is a region of the brain that plays an important role in the integration of sensory perception and motor output.

and

A sex organ, or primary sexual characteristic, narrowly defined, is any of those parts of the body (which are not always bodily organs according to the strict definition) which are involved in sexual reproduction and constitute the reproductive system in a complex organism;

and cannibinoid receptors are absent in:

The medulla oblongata is the lower portion of the brainstem. By anatomical terms of location, it is rostral to the spinal cord and caudal to the pons, which is in turn ventral to the cerebellum.

(This fact means...)

there is not a risk of respiratory or cardiovascular failure as there is with many other drugs.


(that was CB1's, CB2's, found mostly in the spleen affect your immune system.)

[beachguy in thongs]

Aww, man, I wanted to add another 's'!

[beachguy in thongs]

Aren't anadamides just vehicles for the receptors to interact with?

Neurotransmitters are chemicals that are used to relay, amplify and modulate electrical signals between a neuron and another cell

[Edgar]

http://dictionary.reference.com/search?r=2&q=anandamide


http://en.wikipedia.org/wiki/Anandamide

Anandamide, also known as arachidonoylethanolamine or AEA, is a naturally occurring endogenous cannabinoid neurotransmitter found in the brain of animals, as well as other organs.

[beachguy in thongs]

Yeah, that's what I mean, a cannibinoid "neurotransmitter". Not a cannibinoid.

[Edgar]

It's a cannabinoid and a neurotransmitter.

[Edgar]

endogenous cannabinoid neurotransmitter*

[Edgar]

Though I believe all cannabinoids must be neurotransmitters in order for them to be classified as cannabinoids.

[beachguy in thongs]

This is what anandamides bind to. Is this what weed-smoke can do?

In cell biology, G-protein-coupled receptors (also known as GPCRs, seven transmembrane receptors, heptahelical receptors, or 7TM receptors) are transmembrane receptors that transduce an extracellular signal (ligand binding) into an intracellular signal (G protein activation). The GPCR protein superfamily is the largest protein family known, members of which are involved in all types of stimulus-response pathways, from intercellular communication to physiological senses. The diversity of functions is matched by the wide range of ligands recognized by members of the family, from photons (rhodopsin, the archetypal GPCR) to small molecules (in the case of the histamine receptors) to proteins (for example, chemokine receptors). This pervasive involvement in nor al biological processes has the consequence of involving GPCRs in many pathological conditions, which has led to GPCRs being the target of 40 to 50% of modern medicinal drugs.[1]

[Edgar]

THC binds to the same receptors that anandamide binds to. (primarily to the CB1 receptor.)