I looked up Specimen Validity testing on the SAMHSA website and this is what it said;

Substituted
A urine specimen is reported substituted when the creatinine concentration is less than 2 mg/dL and the specific gravity is less than or equal to 1.0010 or greater than or equal to 1.0200 on both the initial and confirmatory creatinine tests (i.e., the same colorimetric test may be used to test both aliquots) and on both the initial and confirmatory specific gravity tests (i.e., a refractometer is used to test both aliquots) on two separate aliquots.

This sounds more like a diluted specimen unless a lot of the sythetic products are low in these chemicals.

I also checked the Genetic Information Nondiscrimination Act and I am a little confused. Is this reinforcing the law that has been around for years or has it changed it for the worse?

Whats the reason why youre taking a U/A for a doctor?
I recently went to the ER for sypmtoms that I had never experienced before, I have been taking Klonopin because I have been going through some extreme stress lately(became disabled, lost job, lost house, wife divorced me and to many things to list). The doctor thinks the symptoms I had were caused by withdrawal from Klonopin, but I have only been taking it for three months, .5mg 4xday. and I quite taking them even though they prescribed them in the hospital. It has been 11 days now and I have experienced no symptoms, so I am defintely not addicted, yet my doctor wants me off of them and he is going to test me to make sure. I am still going through A LOT of stress and I need them and do not intend to quit. I also smoke here and there and I do not want that to show up either, otherwise he will probably recommend going to a rehab facility, which I do not need, since I am not addicted to anything.

So the questions still is, does sythetic urine work or have they passed laws that would allow labs to verify that it is real?