Quote Originally Posted by beachguy in thongs
I'll find proof.

To be precise, according to the Office of Technological Assessment (OTA): "The capacity to produce reinforcing effects is essential to any drug with significant abuse potential." Marijuana should no longer be considered a serious drug abuse because, as summarized by the OTA: "Animals will not self-administer THC in controlled studies . . . . Cannabinoids generally do not lower the threshold needed to get animals to self-stimulate the brain regard system, as do other drugs of abuse." Marijuana does not produce reinforcing effects. The definitive experiment which measures drug-induced dopamine production utilizes microdialysis is live, freely-moving rats. Brain microdialysis has proven that opiates, cocaine, amphetamines, nicotine and alcohol all affect dopamine production, whereas marijuana does not. This latest research confirms and explains Hollister's 1986 conclusion about cannabis and addiction: "Physical dependence is rarely encountered in the usual patterns, despite some degree of tolerance that may develop." Most important, the discoveries of Howlett and Devane, Herkenham and their associates demonstrate that the cannabinoid receptors do not influence the dopamine reward system.
beachguy in thongs Reviewed by beachguy in thongs on . Tolerance: The biggest bitch ever As everyone well knows with extended use and enjoyment of THC (marijuana, pot, hash, cannabis, etc.) every human develops a tolerance to the feeling of being high. As this might be untrue with some lucky individuals, the majority of us started to develop a tolerance at the time when we started to smoke more. Now, the reason I made this post is because I wanted to see if other people have similar issues with tolerance. When I first smoked pot, I became so high and it was so unfamiliar to me I Rating: 5