glass holds up better but harder to drill for filtration
acrylic does scractch e-z,I scrachted a 500 gal saltwater tank at my store.Spent the next 2 weeks with kids pointing at me as i buffed it out."look at the funny fish kids,oh he's a big one".
Anyway the tank I have now is the best IMO,it's got a glass front & acrylic everywhere else.