I tried it once at 12mgs. WAY to much. Great visuals, but nausea on the way up, and a headache on the way down. And both were probably the worst I've ever had, with or without drugs. No plans to try it again, at least not at that dose. But the guys I tripped with {6mgs each) like it. Start with a low dose. And have a whole day clear, lasts forever.