yo i read somthing in a book a while ago and this scientist gave 3 people a pair of glasses that flipped their world upside down........they had to wear these glasses all the time and after like 3 or 5 days what they were seeing was considered normal to them and they could function completly fine even though they were seeing things upside down......so i guess if you write upside down you would get used to it....unless you had upside down and normal letters in there.