well in my experience anti-depressants are very strong or anything so yo uwould have to take multiples...bout the strongest one (as in how bad it knocked me out) was remaron 45 milligram dose....those things would make me stare at one part of a wall or ceiling or somthing...but i have done everything below me....although i won't do alot of it anymore even if i had the worst day of my life and feel that i need to get high i still wouldn't go back to using most of them.....i still wanna do extacy (Again), ketamine, salvia, acid, shrooms, opium, peyote and that's about it...