hello. your distinction between soul and spirit appears mingled. my belief is that psychoactive chemicals can alter the soul, and for many in a very positive way. for some it is just an awareness which coordinates physicality, while for others it can be deeply controlling for cadence and performance. to me, the spirit is never effected. the spirit remains true to the individual personality. the only affectation upon the spirit may be a happiness from self-awareness of soulful coordination.