once pollinated the plant will concentrate on seed production over anything else. if extracts are your goal then you want that plant to form buds and cover them in trichomes as heavily as possible ....so no males.... yank em.
if you really want to keep them then find another place to put them but you might want to get a tyvek suit or 2. just going in and out of the room can transfer pollen on your clothes, hair etc.