I run my room sealed to keep the moisture in, usually keeping it low enough is an issue. It does allow me to maintain a proper vpd with temps in the mid to high 70s and an RH in the 60s for veg. It's during flower that it can be a challange keeping below 60%. Dropping the temps into the lower 70s during flowering helps as my AC runs more.

Now on the cure side, I have definately had issues. What type of humidifier do you use?