Yes, we make tinctures using alcohol, oil, and glycerin. You can extract directly with any of them and except for glycerin, you can also dissolve BHO, QWISO, QWET, etc oil directly into them.

Glycerin will not do so readily, but is easily produced by both the long cold process and a short hot process. I'll post a procedure for both once I have a chance to sort out enough pictures to demonstrate my points.

As noted, alcohol tinctures burn taken orally if they are full strength. If you reduce the amount of alcohol in it, at some point the percentage of alcohol is low enough that it no longer burns, but isn't all that tasty.

I use a sublingual potion for my own medication that I named Holy Shit. It is basically oil with coconut oil, cinnamon oils and gum myrrh added to make it flow, improve the taste, and uptake faster. You might also do a search for that and give it a try.